Best CBD Brands for Treating Epilepsy

Several CBD brands are popular for treating epilepsy. Charlotte’s Web was made famous by helping a girl named Charlotte Figi battle life-threatening seizures, which helped make CBD legal federally. Haleigh’s Hope helped a girl named Haleigh survive seizures and pushed for the legalization of CBD products in Georgia with the 2015 Haleigh’s Hope act. Palmetto Harmony echoes a similar story of treating the seizures of a girl, namedHarmony, and promoting the legalization of CBD in the Palmetto State (the official nickname of South Carolina).

What’s Special About These Brands?

By now, you’ve probably heard that CBD may treat epilepsy and that there’s an FDA-approved CBD medication called Epidiolex. However, CBD-rich hemp extracts that include multiple cannabinoids may outperform pure CBD alone. Researchers refer to this phenomenon as the “entourage effect.” The entourage effect is the recognition that other cannabinoids or nutrients in hemp extract are adding to or enhancing the medicinal benefits of CBD. However, we don’t know what specific hemp compounds are responsible for improving CBD’s treatment of epilepsy.

Our Lab Tests Found CBC and CBG

Our lab tests found that Charlotte’s Web, Haleigh’s Hope, and Palmetto Harmony all contained substantial amounts of the cannabinoids CBC and CBG. There are over a hundred cannabinoids and many different compounds could be responsible for the success of these brands. However, research shows that bothCBC and CBG may help.


Research suggests that cannabichromene (CBC) may treat neurological disorders, inflammation, pain, and depression. CBC also increases THC absorption in the brain while, at the same time, it reduces the side effects of THC (intoxication or “high”). A 2019 study found that a CBD extract with high levels of CBC helped reduce seizures. However, more research is needed to confirm that CBC was partially responsible. Nonetheless, it's a promising new epilepsy treatment. 


New research suggests that cannabigerol (CBG) is a potential treatment for epilepsy and for other neurological conditions. CBG reduces neuroinflammation and oxidative stress; although, CBG is best known for pain relief. It is so powerful that one study found that CBG provides better pain relief than THC.

Other Brands High in CBC and CBG

Bluebird Botanicals is another CBD brand that has high levels of both CBC and CBG.Bluebird is a trustworthy brand that also has a higher “Value Score” than the brands above. Lazarus Naturals has even more CBC and CBG than Bluebird and it’s cheaper, but doesn’t have Bluebird’s accolades.

Headshot of Jeremy Orozco, founder of CBD Examine
Author: Jeremy Orozco

Jeremy is a former firefighter turned health writer. He is a co-founder of CBD Examine and, where he pioneered CBD and migraine research. His latest book, Hemp for Migraine, was the largest collection of peer-reviewed research relating to CBD, cannabinoids, and migraine relief.

This site does not provide medical advice, diagnosis or treatment. Our content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Read the disclaimer.
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